Ib pab neeg Asmeskas tawm tswv yim txoj hauv kev tshiab rau kev kho cov microdisk lasers

Ib pab pawg tshawb fawb ua ke los ntawm Harvard Medical School (HMS) thiab MIT General Hospital hais tias lawv tau ua tiav kev kho qhov tso zis ntawm lub microdisk laser siv txoj kev PEC etching, ua rau qhov chaw tshiab rau nanophotonics thiab biomedicine "muaj kev cia siab."

(Qhov tso zis ntawm lub microdisk laser tuaj yeem hloov kho los ntawm PEC etching txoj kev)

Nyob rau hauv cov teb ntawmnanophotonicsthiab biomedicine, microdiskcov lasersthiab nanodisk lasers tau dhau los ua qhov muaj kev cia siabcov chaw teeb pom kev zoothiab cov probes. Hauv ntau daim ntawv thov xws li kev sib txuas lus photonic ntawm-chip, bioimaging ntawm-chip, biochemical sensing, thiab quantum photon cov ntaub ntawv ua tiav, lawv yuav tsum ua tiav cov zis laser hauv kev txiav txim siab wavelength thiab ultra-narrow band qhov tseeb. Txawm li cas los xij, nws tseem nyuaj rau tsim cov microdisk thiab nanodisk lasers ntawm qhov wavelength meej no ntawm qhov loj. Cov txheej txheem nanofabrication tam sim no qhia txog qhov randomness ntawm disc txoj kab uas hla, uas ua rau nws nyuaj rau tau txais qhov teeb tsa wavelength hauv laser pawg ua thiab tsim khoom. Tam sim no, ib pab pawg neeg tshawb fawb los ntawm Harvard Medical School thiab Massachusetts General Hospital's Wellman Center rauKev Kho Mob Optoelectronictau tsim ib txoj kev siv optochemical (PEC) etching tshiab uas pab kho qhov laser wavelength ntawm microdisk laser kom raug nrog qhov tseeb subnanometer. Cov haujlwm tau luam tawm hauv phau ntawv xov xwm Advanced Photonics.

Kev siv tshuaj photochemical etching
Raws li cov lus ceeb toom, pab neeg txoj kev tshiab no ua rau muaj peev xwm tsim cov micro-disk lasers thiab nanodisk laser arrays nrog cov wavelengths emission uas raug thiab tau teem tseg. Qhov tseem ceeb rau qhov kev tshawb pom no yog kev siv PEC etching, uas muab txoj hauv kev zoo thiab scalable los kho qhov wavelength ntawm microdisc laser. Hauv cov txiaj ntsig saum toj no, pab neeg tau txais indium Gallium arsenide phosphating microdisks uas npog nrog silica ntawm cov qauv indium phosphide. Tom qab ntawd lawv tau kho qhov wavelength laser ntawm cov microdisks no kom raug rau tus nqi txiav txim siab los ntawm kev ua photochemical etching hauv cov tshuaj sulfuric acid diluted.
Lawv kuj tau tshawb nrhiav cov txheej txheem thiab cov dynamics ntawm cov duab tshwj xeeb photochemical (PEC) etchings. Thaum kawg, lawv tau hloov cov wavelength-tuned microdisk array mus rau ib lub polydimethylsiloxane substrate los tsim cov khoom laser ywj pheej, cais nrog cov laser wavelengths sib txawv. Cov microdisk tshwm sim qhia txog ultra-wideband bandwidth ntawm laser emission, nrog raulaserntawm lub kem tsawg dua 0.6 nm thiab cov khoom me me uas raug cais tawm tsawg dua 1.5 nm.

Qhib lub qhov rooj rau cov ntawv thov biomedical
Qhov tshwm sim no qhib lub qhov rooj rau ntau yam nanophotonics tshiab thiab kev siv biomedical. Piv txwv li, cov microdisk lasers sawv ntsug tuaj yeem ua haujlwm ua cov barcodes physico-optical rau cov qauv biological heterogeneous, ua rau muaj kev sau npe ntawm cov hom cell tshwj xeeb thiab kev tsom mus rau cov molecules tshwj xeeb hauv kev tshuaj xyuas multiplex. Kev sau npe tshwj xeeb ntawm hom cell tam sim no ua tiav los ntawm kev siv cov cim biomarkers ib txwm muaj, xws li cov organic fluorophores, quantum dots, thiab fluorescent beads, uas muaj cov kab dav dav. Yog li, tsuas yog ob peb hom cell tshwj xeeb tuaj yeem sau npe tib lub sijhawm. Qhov sib piv, qhov ultra-narrow band lub teeb emission ntawm microdisk laser yuav tuaj yeem txheeb xyuas ntau hom cell tib lub sijhawm.
Cov pab pawg neeg tau sim thiab ua tiav qhov kev ua tau zoo ntawm cov khoom me me microdisk laser uas tau kho kom raug raws li cov cim qhia, siv lawv los sau cov hlwb epithelial ntawm lub mis MCF10A. Nrog lawv cov kev tso tawm ultra-wideband, cov lasers no tuaj yeem hloov pauv biosensing, siv cov txheej txheem biomedical thiab optical uas tau ua pov thawj xws li cytodynamic imaging, flow cytometry, thiab multi-omics analysis. Cov thev naus laus zis raws li PEC etching cim qhov kev nce qib loj hauv microdisk lasers. Qhov scalability ntawm txoj kev, nrog rau nws qhov kev ua haujlwm subnanometer, qhib cov cib fim tshiab rau kev siv ntau yam ntawm lasers hauv nanophotonics thiab biomedical devices, nrog rau barcodes rau cov pej xeem cell tshwj xeeb thiab cov molecules analytical.