Cov ntsiab lus ntawm photoacoustic imaging

Cov ntsiab lus ntawm photoacoustic imaging

Photoacoustic Imaging (PAI) yog cov txheej txheem kho mob uas ua keopticsthiab acoustics los tsim cov cim ultrasonic siv kev sib cuam tshuam ntawmteebnrog cov ntaub so ntswg kom tau txais cov ntaub so ntswg zoo. Nws yog dav siv nyob rau hauv biomedical teb, tshwj xeeb tshaj yog nyob rau hauv lub qog nrhiav, vascular imaging, daim tawv nqaij imaging thiab lwm yam teb.

Txoj Cai:
1. Lub teeb haum thiab thermal expansion: - Photoacoustic imaging siv cov thermal nyhuv uas ua los ntawm lub teeb nqus. Cov xim molecules nyob rau hauv cov ntaub so ntswg (xws li, hemoglobin, melanin) nqus photons (feem ntau nyob ze-infrared lub teeb), uas yog hloov mus rau hauv tshav kub zog, ua rau lub zos kub nce.
2. Thermal expansion ua ultrasound: - Kub nce ua rau me me thermal expansion ntawm cov ntaub so ntswg, uas ua rau lub siab tsis (ie ultrasound).
3. Ultrasonic nrhiav kom tau: – Cov generated ultrasonic tsis propagate nyob rau hauv cov ntaub so ntswg, thiab cov teeb liab no tom qab tau txais thiab kaw los ntawm ultrasonic sensors (xws li ultrasonic probes).
4. Kev tsim kho duab: cov teeb liab ultrasonic sau tau suav thiab ua tiav los tsim kho cov qauv thiab kev ua haujlwm ntawm cov ntaub so ntswg, uas tuaj yeem muab cov yam ntxwv kho qhov muag ntawm cov ntaub so ntswg. Qhov zoo ntawm photoacoustic imaging: High contrast: Photoacoustic imaging cia siab rau lub teeb nqus cov yam ntxwv ntawm cov ntaub so ntswg, thiab cov ntaub so ntswg sib txawv (xws li ntshav, rog, nqaij, thiab lwm yam) muaj peev xwm sib txawv los nqus lub teeb, yog li nws muaj peev xwm muab high-zoo dluab. Kev daws teeb meem siab: Siv lub siab spatial daws teeb meem ntawm ultrasound, photoacoustic imaging tuaj yeem ua tiav millimeter lossis txawm tias sub-millimeter imaging raug. Non-invasive: Photoacoustic imaging yog non-invasive, lub teeb thiab suab yuav tsis ua rau cov ntaub so ntswg puas, haum rau tib neeg kev kho mob. Kev muaj peev xwm ua kom pom qhov tob: Piv nrog cov duab kho qhov muag, cov duab thaij duab tuaj yeem nkag mus rau ob peb centimeters hauv qab ntawm daim tawv nqaij, uas yog tsim rau cov ntaub so ntswg sib sib zog nqus.

Daim ntawv thov:
1. Vascular imaging: - Photoacoustic imaging tuaj yeem kuaj xyuas lub teeb-absorbing ntawm hemoglobin hauv cov ntshav, yog li nws tuaj yeem pom tseeb cov qauv thiab oxygenation ntawm cov hlab ntsha rau kev saib xyuas cov kab mob microcirculation thiab kev txiav txim siab.
2. Kev kuaj qog nqaij hlav: - Angiogenesis hauv cov qog nqaij hlav feem ntau muaj ntau heev, thiab cov duab photoacoustic tuaj yeem pab tshawb pom cov qog thaum ntxov los ntawm kev kuaj pom qhov txawv txav ntawm cov hlab ntsha.
3. Kev pom kev ua haujlwm: - Photoacoustic imaging tuaj yeem ntsuas cov pa oxygen ntawm cov ntaub so ntswg los ntawm kev kuaj xyuas cov pa oxygenation thiab deoxyhemoglobin hauv cov ntaub so ntswg, uas yog qhov tseem ceeb rau kev saib xyuas cov kab mob xws li mob qog noj ntshav thiab kab mob plawv.
4. Daim tawv nqaij imaging: - Vim photoacoustic imaging yog rhiab heev rau cov ntaub so ntswg superficial, nws yog haum rau thaum ntxov kuaj ntawm daim tawv nqaij mob cancer thiab tsom xam ntawm daim tawv nqaij txawv txav.
5. Kev kuaj pom lub hlwb: Kev thaij duab photoacoustic tuaj yeem tau txais cov ntaub ntawv ntawm cov hlab ntsha hauv hlwb uas tsis cuam tshuam rau kev kawm txog kab mob hlwb xws li mob stroke thiab mob vwm.

Kev sib tw thiab kev txhim kho cov lus qhia ntawm photoacoustic duab:
Lub teeb qhov chawkev xaiv: Lub teeb nkag mus ntawm qhov sib txawv wavelength yog qhov sib txawv, yuav ua li cas xaiv qhov kev daws teeb meem wavelength thiab qhov tob tob yog qhov nyuaj. Kev ua cov teeb liab: Kev nrhiav tau thiab ua tiav ntawm cov teeb liab ultrasonic xav tau kev kub ceev thiab raug algorithms, thiab kev txhim kho cov duab tsim kho tshuab kuj tseem ceeb heev. Multimodal imaging: Photoacoustic imaging tuaj yeem ua ke nrog lwm yam kev ntsuas (xws li MRI, CT, ultrasound imaging) kom muab cov ntaub ntawv qhia txog biomedical ntau dua.

Photoacoustic imaging yog ib qho tshiab thiab ntau txoj haujlwm biomedical imaging technology, uas muaj cov yam ntxwv ntawm qhov sib txawv siab, siab daws teeb meem thiab tsis cuam tshuam. Nrog rau kev txhim kho thev naus laus zis, kev yees duab photoacoustic muaj cov ntawv thov dav dav hauv kev kuaj mob, kev tshawb fawb txog biology, kev tsim tshuaj thiab lwm yam haujlwm.